Fibroblast USA



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Product Features
COLLIUM is a compound term that combines "Collagen" and "Volume," signifying its purpose to create voluminous skin in conjunction with collagen.
Collagen is a primary protein component of our body's connective tissues (blood vessels, bones, teeth, muscles, etc.), and it plays an important role in various aspects, including skin beauty, preventing arterial hardening, and improving joint health.
The main ingredient in Collium is Atelo Collagen, which closely matches the collagen found in the skin's epidermis, with a 99% similarity. It has removed antigenic telopeptides to minimize immune reactions. It fills collagen into sagging skin, not only creating volume but also activating the generation and metabolism of other skin cells. This aids in improving skin tone and enhancing skin elasticity.

Benefits and Effects
- Biocompatibility
- Skin Rejuvenation
- Versatile Applications

Active Ingredients
Atelo Collagen 30mg/ml

Areas of Application
- Whole face
- Neck
- Back of hands
* The maximum recommended amount per treatment is 1ml.

How to Use
1. Mesotherapy Treatment
Injecting Collium into the entire epidermal or basal layers of the face is a suitable treatment method for clients seeking overall skin rejuvenation, healing of acne scars, achieving firmer and smoother skin, and improving skin tone. This method can address general skin damage and promote a more youthful and even complexion.
It is possible to procedure with the Meso gun which allows for pre-setting of depth and volume or the Nappage Technique, which injects into the epidermal layer, and the Papule Technique, which injects into the basal layer.

2. Collagen Injectable Biostimulator
While most HA (Hyaluronic Acid) fillers can be injected from the epidermal layer to the muscular fascial layer based on the client's needs, Collium, due to its product characteristics, injections deeper than the epidermal are not recommended

- Collium
It is possible to inject Collium into the dermis layer of the skin, and it's important to inject small amounts thinly.
* 1ml Collium can be used for the whole face.
However, more ml of Collium is required to achieve the same effect when injected deeply, so it is not recommended. Additionally, injecting wrong too deep can lead to side effects such as nodules, so it is recommended to perform injections maximum of 1ml per session.

- Collium + Reglory PDRN
It is recommended to combine Collium with skin booster products or non-crosslinked HA (Hyaluronic Acid) products such as Relory PDRN, Kiara Reju, or Hyaron. 
Mixing these products can contribute to various improvements in the skin, including enhanced skin elasticity, wrinkle reduction, skin rejuvenation, and skin brightening.
Steps for Procedure:
1. Thoroughly disinfect the treatment area before the procedure.
2. Apply the topical anesthesia if necessary.
3. Use a disposable Syringe Mixing Tube to mix around 6 times.
4. Insert needles into the syringe.
5. Inject the predetermined amount into the treatment area according to the physician's judgment.
6. After injection, massage the treatment area to ensure even distribution of the injected substance.

Treatment Interval
4 treatments at intervals of 3 months

Recommended Needle Gauge


Syringe: 1ml x 1ea

Expiry Date
36 months from the production date.

Storage Temperature
- Please keep away from direct sunlight.
- Store in a cool, dry place at a temperature of 2 to 28 ℃.

Warnings and Precautions
This product should only be used by trained professionals or doctors.
This product is a medical device. Customs clearance may be difficult depending on each country's rules and regulations. So please check the customs clearance situation in each country before ordering.

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